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On regression analysis, hypoperfused volumes on CTP were associated with excellent outcomes (odds ratio [OR] 1.02, 95% confidence intervals [CI] 1.001-1.037) whereas core volume was not

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Depending on the symptoms, kratom-related overdose has been managed with the μ -opioid receptor antagonist naloxone to reverse the opioid-like effects (either from kratom or coingested opioids), whereas the dual α and β adrenergic antagonist labetalol has been used to manage sympathetic overactivation (Peran et al., 2023)